Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors

Sigma receptors (SRs), including SR1 and SR2 subtypes, have attracted increasing interest in recent years due to their involvement in a wide range of activities, including the modulation of opioid analgesia, neuroprotection, and potential anticancer activity. In this context, haloperidol (HAL), a co...

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Autors principals:	Daniele Zampieri, Maurizio Romano, Sara Fortuna, Emanuele Amata, Maria Dichiara, Giuseppe Cosentino, Agostino Marrazzo, Maria Grazia Mamolo
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-06-01
Col·lecció:	Molecules
Matèries:	sigma 1 receptor sigma 2 receptor anticancer affinity selectivity docking
Accés en línia:	https://www.mdpi.com/1420-3049/29/11/2697
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