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Phospholipase A and acyltransferase 4/retinoic acid receptor responder 3 at the intersection of tumor suppression and pathogen restriction

Phospholipase A and acyltransferase (PLAAT) 4 is a class II tumor suppressor with phospholipid metabolizing abilities. It was characterized in late 2000s, and has since been referred to as ‘tazarotene-induced gene 3’ (TIG3) or ‘retinoic acid receptor responder 3’ (RARRES3) as a key downstream effect...

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Principais autores: Jian-Yong Zhao, Xiang-Kun Yuan, Rui-Zhen Luo, Li-Xin Wang, Wei Gu, Daisuke Yamane, Hui Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-03-01
coleção:Frontiers in Immunology
Assuntos:
retinoic acid
class II tumor suppressor
lipid metabolizing enzyme
p53
IRF1
interferon
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107239/full
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