The Recombinant Bacille Calmette–Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing

The only licensed vaccine against tuberculosis (TB), bacille Calmette–Guérin (BCG), protects against severe extrapulmonary forms of TB but is virtually ineffective against the most prevalent form of the disease, pulmonary TB. BCG was genetically modified at the Max Planck Institute for Infection Bio...

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Principais autores:	Natalie E. Nieuwenhuizen, Prasad S. Kulkarni, Umesh Shaligram, Mark F. Cotton, Cyrill A. Rentsch, Bernd Eisele, Leander Grode, Stefan H. E. Kaufmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-09-01
coleção:	Frontiers in Immunology
Assuntos:	tuberculosis bacille Calmette–Guérin VPM1002 vaccine listeriolysin immune response
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01147/full
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