Targeting the Tumor Microenvironment with Gene-Engineered Immune Cells: Focus on CAR-Macrophages and CAR-NK Cells – A Review Article
The TME is a culprit of immunosuppression and a significant hurdle to long-term immunotherapeutic success in solid tumors, which are often associated with a dense stroma, hypoxia, and immunosuppressive myeloid and lymphoid cells. Conventional CAR-T cells tend to fail in this scenario as they are su...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Health Innovation Press
2025-10-01
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| Serie: | Health Innovation Reports |
| Soggetti: | |
| Accesso online: | https://healthinnovationpress.com/index.php/hir/article/view/54 |
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