A comprehensive analysis of humanized mouse models for the study of cancer immunotherapies

IntroductionHumanized immune system (HIS) mouse models, generated by engrafting tumors and hematopoietic cells of human (Hu) origin into immunodeficient host mice, effectively recapitulate key aspects of the crosstalk between human immune cells and tumors. These models represent a valuable tool for...

Descripció completa

Dades bibliogràfiques

Autors principals:	Philippe De La Rochere, Laure Loumagne, Melanie Rathaux, Marine Dubois, Jordan Denizeau, Fariba Nemati, Sophie Viel, Dario Rocha, Tamara Slavnic, Jayant Thatte, Henry Qixiang Li, Xuesong Ouyang, Christine Sedlik, Didier Decaudin, Georges Azar, Sukhvinder Sidhu, Eliane Piaggio
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	cancer humanized mice immune checkpoints immunodeficient mice immunotherapy
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1730378/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!