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A Live‐Cell Epigenome Manipulation by Photo‐Stimuli‐Responsive Histone Methyltransferase Inhibitor

Abstract Post‐translational modifications on the histone H3 tail regulate chromatin structure, impact epigenetics, and hence the gene expressions. Current chemical modulation tools, such as unnatural amino acid incorporation, protein splicing, and sortase‐based editing, have allowed for the modifica...

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Detalles Bibliográficos
Principais autores: Chuan‐Shuo Wu, Xin Sun, Li Liu, Liang Cheng
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2024-11-01
Series:Advanced Science
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Acceso en liña:https://doi.org/10.1002/advs.202404608
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