Mapping Regioisomer-Dependent Buchwald–Hartwig C-N Coupling: Bromoimidazo[1,5-a]pyridines as a Model Electrophile Series

Buchwald–Hartwig C-N coupling is a central method for constructing (hetero)aryl–nitrogen bonds. Yet condition translatability is often problematic from one substrate to another, even among closely related substrates, especially for heteroaryl halides. In this work, we demonstrate an approach to solv...

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Detalhes bibliográficos

Principais autores:	Svitlana O. Sotnik, Svitlana V. Stetsenko, Illia M. Pavliei, Oleksii A. Brusylovets, Oleksandr A. Pokholenko, Galyna P. Grabchuk, Olexandr Ye. Pashenko, Dmytro M. Volochnyuk, Serhiy V. Ryabukhin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-07-01
coleção:	Molecules
Assuntos:	Buchwald–Hartwig reaction C-N cross-coupling high-throughput screening heteroaryl bromides imidazo[1,5-a]pyridine palladium catalysis
Acesso em linha:	https://www.mdpi.com/1420-3049/31/13/2339
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