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GPX4 activator enhances neuroprotection and functional recovery in spinal cord injury

Background: Spinal cord injury (SCI) exerts severe physical, social, and economic effects on individuals and the healthcare system. While much progress has been made in understanding the pathophysiology of SCI, the regulation of the ferroptosis master regulator, GPX4 (Glutathione Peroxidase 4), rema...

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Principais autores: Xinjie Liu, Yilin Pang, Baoyou Fan, Jiawei Zhang, Shen Liu, Xiaobing Deng, Yun Li, Ying Liu, Xu Zhang, Chenxi Zhao, Xiaoyu Wang, Xudong Wu, Luhua Lai, Shiqing Feng, Wenpeng Liu, Guangzhi Ning, Xue Yao
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2025-05-01
Serija:Journal of Orthopaedic Translation
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2214031X2500049X
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