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PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection.

HIV co-infection is an important risk factor for tuberculosis (TB) providing a powerful model in which to dissect out defective, protective and dysfunctional Mycobacterium tuberculosis (MTB)-specific immune responses. To identify the changes induced by HIV co-infection we compared MTB-specific CD4+...

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Principais autores: Katrina M Pollock, Damien J Montamat-Sicotte, Lisa Grass, Graham S Cooke, Moses S Kapembwa, Onn M Kon, Robert D Sampson, Graham P Taylor, Ajit Lalvani
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4710462?pdf=render
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