COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidome

Abstract Background Neoantigens have emerged as a promising area of focus in tumor immunotherapy, with several established strategies aiming to enhance their identification. Human leukocyte antigen class I molecules (HLA-I), which present intracellular immunopeptides to T cells, provide an ideal sou...

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Principais autores:	Fangzhou Wang, Zhenpeng Zhang, Mingsong Mao, Yudai Yang, Ping Xu, Shichun Lu
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2024-02-01
סדרה:	Journal of Translational Medicine
נושאים:	HLA immunopeptidome Neoantigen identification HepG2 cell COSMIC database Hepatocellular carcinoma
גישה מקוונת:	https://doi.org/10.1186/s12967-023-04821-0
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