Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis
Abstract SapM is a secreted virulence factor from Mycobacterium tuberculosis critical for pathogen survival and persistence inside the host. Its full potential as a target for tuberculosis treatment has not yet been exploited because of the lack of potent inhibitors available. By screening over 1500...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2021-04-01
|
| Collection: | Scientific Reports |
| Accès en ligne: | https://doi.org/10.1038/s41598-021-87117-x |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|