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Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis

Abstract Tuberculosis pleural effusion (TPE) accounts for 30 ~ 80% of all pleural effusions in developing countries and remains a major contributor to global morbidity and mortality. Although TPE is often absorbed after anti-tuberculosis treatment, approximately 60% of patients develop pleural thick...

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Principais autores: Li-Juan Jiang, Yuan-Yi Zheng, Li-Mei Liang, Zi-Heng Jia, Rong-Hui Du, Hai Huang, Xiyong Dai, Pei-Pei Cheng, Li-Qin Zhao, Qian Li, Ye-Han Jiang, Xiao-Lin Cui, Shu-Yi Ye, Shi-He Hu, He-De Zhang, Chen-Yue Lian, Xiao Feng, Lin-Jie Song, Fan Yu, Xin-Liang He, Liang Xiong, Fei Xiang, Xiaorong Wang, An-Dong Liu, Meng Wang, Hong Ye, Wan-Li Ma
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-02-01
coleção:Respiratory Research
Assuntos:
Exosome
microRNAs
Tuberculous pleural effusion
TGF-β
Pleural fibrosis
Acesso em linha:https://doi.org/10.1186/s12931-026-03541-5
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