Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

ABSTRACT Lipid nanoparticles (LNPs) are widely used for nucleic acid delivery, yet their clinical utility is limited by an acute inflammatory response post‐administration. LNP‐associated inflammation (LAI) manifests as de novo inflammation in select organs (e.g., in the lungs after inhalation) and s...

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Detaylı Bibliyografya
Asıl Yazarlar:	Carolann L. Espy, Jichuan Wu, Serena Omo‐Lamai, Liuqian Wang, Fengyi Dong, Aleksa Milosavljevic, Sarah O'Neill, Taylor Brysgel, Yufei Wang, Michael Zaleski, Emily Wolfe, Rhea Maheshwari, Manthan Patel, Dirk Trauner, Jia Nong, Zhicheng Wang, Jacob S. Brenner
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Wiley 2026-06-01
Seri Bilgileri:	Advanced Science
Konular:	inflammation nanoparticles NF‐κB inhibition small molecule drug loading
Online Erişim:	https://doi.org/10.1002/advs.202517931
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

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