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Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei

We have discovered a new mechanism of monoallelic gene expression that links antigenic variation, cell cycle, and development in the model parasite Trypanosoma brucei. African trypanosomes possess hundreds of variant surface glycoprotein (VSG) genes, but only one is expressed from a telomeric expres...

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Auteurs principaux: Christopher Batram, Nicola G Jones, Christian J Janzen, Sebastian M Markert, Markus Engstler
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications Ltd 2014-05-01
Collection:eLife
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Accès en ligne:https://elifesciences.org/articles/02324
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