Transcription factor NF-kappaB is transported to the nucleus via cytoplasmic dynein/dynactin motor complex in hippocampal neurons.

Long-term changes in synaptic plasticity require gene transcription, indicating that signals generated at the synapse must be transported to the nucleus. Synaptic activation of hippocampal neurons is known to trigger retrograde transport of transcription factor NF-kappaB. Transcription factors of th...

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Autors principals:	Ilja Mikenberg, Darius Widera, Aljoscha Kaus, Barbara Kaltschmidt, Christian Kaltschmidt
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2007-07-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC1899224?pdf=render
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