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KSHV infection of B cells primes protective T cell responses in humanized mice

Abstract Kaposi sarcoma associated herpesvirus (KSHV) is associated with around 1% of all human tumors, including the B cell malignancy primary effusion lymphoma (PEL), in which co-infection with the Epstein Barr virus (EBV) can almost always be found in malignant cells. Here, we demonstrate that KS...

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Principais autores: Nicole Caduff, Lisa Rieble, Michelle Böni, Donal McHugh, Romin Roshan, Wendell Miley, Nazzarena Labo, Sumanta Barman, Matthew Trivett, Douwe M. T. Bosma, Julia Rühl, Norbert Goebels, Denise Whitby, Christian Münz
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-06-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-024-49209-w
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