Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis.

Treatment and control of schistosomiasis relies on the only available drug, praziquantel, and the search for alternative chemotherapeutic agents is therefore urgent. Egg production is required for the transmission and immunopathology of schistosomiasis and females of S. mansoni lay 300 eggs daily. A...

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Autori principali:	Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Eduardo José Lopes Torres, Stephany Caby, Julien Lancelot, Mathieu Vanderstraete, Silviya D Furdas, Manfred Jung, Raymond J Pierce, Marcelo Rosado Fantappié
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2014-05-01
Serie:	PLoS Pathogens
Accesso online:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24809504/pdf/?tool=EBI
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