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Polygenic risk score and 20-year prostate cancer-specific mortality and survival

Abstract Background Polygenic risk scores (PRSs) strongly discriminate for prostate cancer risk at the population level. The role of these genetic scores in determining prostate cancer survival is unclear, potentially due to methodological issues. Methods We included 19,607 men from the Malmö Diet a...

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Hlavní autoři: Anna Plym, Anqi Wang, Konrad H. Stopsack, Yiwen Zhang, Aris Baras, Regeneron Genetics Center, Isabel Drake, Mark Clements, Kathryn L. Penney, Edward Giovannucci, Adam S. Kibel, Lorelei A. Mucci, Fredrik Wiklund
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-04-01
Edice:Communications Medicine
On-line přístup:https://doi.org/10.1038/s43856-026-01603-9
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