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Hexokinase II may be dispensable for CD4 T cell responses against a virus infection.

Activation of CD4 T cells leads to their metabolic reprogramming which includes enhanced glycolysis, catalyzed through hexokinase enzymes. Studies in some systems indicate that the HK2 isoform is the most up regulated isoform in activated T cells and in this report the relevance of this finding is e...

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Principais autores: Siva Karthik Varanasi, Ujjaldeep Jaggi, Nissim Hay, Barry T Rouse
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5774810?pdf=render
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