The mediating effect of circulating inflammatory proteins on the relationship between gut microbiota and FD: a bidirectional Mendelian randomization study

Abstract Functional dyspepsia (FD) is known to be influenced by gut microbiota (GM) and circulating inflammatory proteins (CIPs), however, the causal relationship between GM, CIPs and FD haven’t been investigated. This study employed two-sample Mendelian Randomization (TSMR) to investigate their ass...

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Autori principali:	Li Li, Minhan Fu, Feiyi Chen, Huijie Ji, Guowei Zhou, Lu Chen, Hao Geng, Jing Guo, Lixia Pei, Jianhua Sun
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2024-10-01
Serie:	Scientific Reports
Soggetti:	Mendelian randomization Functional dyspepsia Gut microbiota Circulating inflammatory proteins Mediation analysis
Accesso online:	https://doi.org/10.1038/s41598-024-74717-6
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