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Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate

The virulence of intracellular pathogens relies largely on the ability to survive and replicate within phagocytes but also on release and transfer into new host cells. Such cell-to-cell transfer could represent a target for counteracting microbial pathogenesis. However, our understanding of the unde...

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Detalles Bibliográficos
Principais autores: Iris Baars, Moritz Jaedtka, Leon-Alexander Dewitz, Yan Fu, Tobias Franz, Juliane Mohr, Patricia Gintschel, Hannes Berlin, Angelina Degen, Sandra Freier, Stefan Rygol, Burkhart Schraven, Sascha Kahlfuß, Ger van Zandbergen, Andreas J. Müller
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical investigation 2023-07-01
Series:JCI Insight
Assuntos:
Acceso en liña:https://doi.org/10.1172/jci.insight.169020
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