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Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans

Summary: Obstructive sleep apnea (OSA) induces intermittent hypoxia (IH), an independent risk factor for non-alcoholic fatty liver disease (NAFLD). While the molecular links between IH and NAFLD progression are unclear, immune cell-driven inflammation plays a crucial role in NAFLD pathogenesis. Usin...

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Váldodahkkit: Jonathan Gaucher, Emilie Montellier, Guillaume Vial, Florent Chuffart, Maëlle Guellerin, Sophie Bouyon, Emeline Lemarie, Yoshiki Yamaryo Botté, Aya Dirani, Raoua Ben Messaoud, Marie Joyeux Faure, Diane Godin Ribuot, Charlotte Costentin, Renaud Tamisier, Cyrille Y. Botté, Saadi Khochbin, Sophie Rousseaux, Jean-Louis Pépin
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2024-02-01
Ráidu:iScience
Fáttát:
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2589004224000580
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