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Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression

Abstract Chronological age is an imperfect estimate of molecular aging. Epigenetic age, derived from DNA methylation data, provides a more nuanced representation of aging-related biological processes. We examine the bidirectional relationship between epigenetic age and brain health events (stroke, d...

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Hlavní autoři: Cyprien A. Rivier, Natalia Szejko, Daniela Renedo, Santiago Clocchiatti-Tuozzo, Shufan Huo, Adam de Havenon, Hongyu Zhao, Thomas M. Gill, Kevin N. Sheth, Guido J. Falcone
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-02-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-024-54721-0
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