The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT The innate immune system uses Toll-like receptor (TLR) 2 to detect conserved bacterial lipoproteins of invading pathogens. The lipid anchor attaches lipoproteins to the cytoplasmic membrane and prevents their release from the bacterial cell envelope. How bacteria release lipoproteins and ho...

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Detalles Bibliográficos

Principais autores:	Katja Schlatterer, Christian Beck, Dennis Hanzelmann, Marco Lebtig, Birgit Fehrenbacher, Martin Schaller, Patrick Ebner, Mulugeta Nega, Michael Otto, Dorothee Kretschmer, Andreas Peschel
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2018-12-01
Series:	mBio
Assuntos:	Staphylococcus aureus leukocytes lipoproteins pore-forming toxins Toll-like receptors vesicles
Acceso en liña:	https://journals.asm.org/doi/10.1128/mBio.01851-18
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