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Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

ABSTRACT Aging gradually impairs immune system function, yet its systemic features across immune organs remain poorly characterized in primates. Here, we perform single‐cell transcriptomic profiling of bone marrow, spleen, mesenteric lymph nodes, and peripheral blood mononuclear cells from young and...

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Principais autores: Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-03-01
Serier:Advanced Science
Fag:
immunosenescence
rhesus monkeys
single‐cell
Online adgang:https://doi.org/10.1002/advs.202514353
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