Antimicrobial peptide thanatin fused endolysin PA90 (Tha-PA90) for the control of Acinetobacter baumannii infection in mouse model

Abstract Background This study addresses the urgent need for infection control agents driven by the rise of drug-resistant pathogens such as Acinetobacter baumannii. Our primary aim was to develop and assess a novel endolysin, Tha-PA90, designed to combat these challenges. Methods Tha-PA90 incorpora...

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Autores principales:	Jeonghyun Lim, Heejoon Myung, Daejin Lim, Miryoung Song
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-04-01
Colección:	Journal of Biomedical Science
Materias:	Endolysin Thanatin Tha-PA90 Designed endolysin A. baumannii infection Drug-resistant gram-negative pathogen
Acceso en línea:	https://doi.org/10.1186/s12929-024-01027-4
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