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Raw lacquer-associated familial chronic myelomonocytic leukemia with multi-hit TET2 mutations

BackgroundTo explore the potential association between long-term exposure to raw lacquer and the development of chronic myelomonocytic leukemia (CMML).MethodsWe analyzed the clinical and hematological characteristics of an elderly couple with CMML. Whole-exome sequencing (WES) was performed to ident...

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Principais autores: Yang Zhang, Yujiao Luo, Hongling Peng, Yafei Yin, Guangsen Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-08-01
coleção:Frontiers in Oncology
Assuntos:
raw lacquer
chronic myelomonocytic leukemia
familial
TET2 mutation
Runx1
N-ras
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2025.1605369/full
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