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Promise of the NLRP3 Inflammasome Inhibitors in In Vivo Disease Models

Nucleotide-binding oligomerization domain NOD-like receptors (NLRs) are conserved cytosolic pattern recognition receptors (PRRs) that track the intracellular milieu for the existence of infection, disease-causing microbes, as well as metabolic distresses. The NLRP3 inflammasome agglomerates are cons...

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Main Authors: Biswadeep Das, Chayna Sarkar, Vikram Singh Rawat, Deepjyoti Kalita, Sangeeta Deka, Akash Agnihotri
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
NOD-like receptors
NLRP3
inflammasome
inflammation
disease inhibitor
Online Access:https://www.mdpi.com/1420-3049/26/16/4996
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