9-cis-Retinoic Acid Improves Disease Modelling in iPSC-Derived Liver Organoids

Liver fibrosis majorly impacts global health, necessitating the development of in vitro models to study disease mechanisms and develop drug therapies. Relevant models should at least include hepatocytes and hepatic stellate cells (HSCs) and ideally use three-dimensional cultures to mimic in vivo con...

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書誌詳細

主要な著者:	Mina Kazemzadeh Dastjerd, Vincent Merens, Ayla Smout, Rebeca De Wolf, Christophe Chesné, Catherine Verfaillie, Stefaan Verhulst, Leo A. van Grunsven
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2025-06-01
シリーズ:	Cells
主題:	liver fibrosis DILI hepatic stellate cell activation hepatocytes drug metabolism iPSC
オンライン･アクセス:	https://www.mdpi.com/2073-4409/14/13/983
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