USP10/XAB2/ANXA2 axis promotes DNA damage repair to enhance chemoresistance to oxaliplatin in colorectal cancer

Abstract Background Oxaliplatin-based chemotherapy is the first-line treatment for colorectal cancer (CRC). However, oxaliplatin resistance remains a major challenge contributing to treatment failure and poor prognosis. An increased capacity for DNA damage repair is a key mechanism underlying oxalip...

Descripció completa

Dades bibliogràfiques

Autors principals:	Xingwu Liu, Shaoming Zhang, Yue An, Boyang Xu, Guanyu Yan, Mingjun Sun
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-03-01
Col·lecció:	Journal of Experimental & Clinical Cancer Research
Matèries:	Colorectal cancer Oxaliplatin resistance DNA damage repair Deubiquitination XAB2
Accés en línia:	https://doi.org/10.1186/s13046-025-03357-z
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!