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TAZ reverses the inhibitory effects of LPS on the osteogenic differentiation of human periodontal ligament stem cells through the NF-κB signaling pathway

Abstract Background Human periodontal ligament stem cells (hPDLSCs) are important candidate seed cells for periodontal tissue engineering, but the presence of lipopolysaccharide(LPS) in periodontal tissues inhibits the self-renewal and osteogenic differentiation of hPDLSCs. Our previous studies demo...

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Principais autores: Shuyi Dong, Linglu Jia, Shaoqing Sun, Xingyao Hao, Xiaomei Feng, Yunge Qiu, Ke Gu, Yong Wen
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-06-01
Series:BMC Oral Health
Assuntos:
TAZ
LPS
Human periodontal ligament stem cells
Osteogenic differentiation
NF-κB pathway
Acceso en liña:https://doi.org/10.1186/s12903-024-04497-y
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