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High-Throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants during Acute Infection.

Pathogenic species of Leptospira are the causative agents of leptospirosis, a zoonotic disease that causes mortality and morbidity worldwide. The understanding of the virulence mechanisms of Leptospira spp is still at an early stage due to the limited number of genetic tools available for this micro...

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Autori principali: Kristel Lourdault, James Matsunaga, David A Haake
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-11-01
Serie:PLoS Neglected Tropical Diseases
Accesso online:http://europepmc.org/articles/PMC5100919?pdf=render
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