Sulfide (Na₂S) and Polysulfide (Na₂S₂) Interacting with Doxycycline Produce/Scavenge Superoxide and Hydroxyl Radicals and Induce/Inhibit DNA Cleavage

Doxycycline (DOXY) is an antibiotic routinely prescribed in human and veterinary medicine for antibacterial treatment, but it has also numerous side effects that include oxidative stress, inflammation, cancer or hypoxia-induced injury. Endogenously produced hydrogen sulfide (H₂S) and poly...

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Autors principals:	Anton Misak, Lucia Kurakova, Eduard Goffa, Vlasta Brezova, Marian Grman, Elena Ondriasova, Miroslav Chovanec, Karol Ondrias
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2019-03-01
Col·lecció:	Molecules
Matèries:	hydrogen sulfide polysulfides doxycycline oxytetracycline tetracycline superoxide hydroxyl radical DNA cleavage EPR spectroscopy <sup>•</sup>cPTIO radical
Accés en línia:	https://www.mdpi.com/1420-3049/24/6/1148
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