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Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation

The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripotency and early development. Mof is the enzymatic subunit of two different HAT complexes, MSL and NSL. The individual contribution of MSL and NSL to transcription regulation in mESCs is not well understo...

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Principais autores: Sarina Ravens, Marjorie Fournier, Tao Ye, Matthieu Stierle, Doulaye Dembele, Virginie Chavant, Làszlò Tora
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2014-06-01
coleção:eLife
Assuntos:
histone acetyltransferase
Mof (KAT8)
H4K16ac
pluripotency
bivalent domain
ChIP-seq
Acesso em linha:https://elifesciences.org/articles/02104
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