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The myocardium utilizes a platelet-derived growth factor receptor alpha (Pdgfra)–phosphoinositide 3-kinase (PI3K) signaling cascade to steer toward the midline during zebrafish heart tube formation

Coordinated cell movement is a fundamental process in organ formation. During heart development, bilateral myocardial precursors collectively move toward the midline (cardiac fusion) to form the primitive heart tube. Extrinsic influences such as the adjacent anterior endoderm are known to be require...

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Bibliografiske detaljer
Principais autores: Rabina Shrestha, Tess McCann, Harini Saravanan, Jaret Lieberth, Prashanna Koirala, Joshua Bloomekatz
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2023-11-01
Serier:eLife
Fag:
Online adgang:https://elifesciences.org/articles/85930
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