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Activation of TC10-Like Transcription by Lysine Demethylase KDM4B in Colorectal Cancer Cells

Malignant colorectal cancers (CRCs) are characterized by enhanced migration and invasion thus acquiring the ability to metastasize. We have previously shown that the small GTPase TC10-like (TCL) contributes to aggressive migration and invasion in malignant CRC cells. TCL expression is differentially...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Baoyu Chen, Yuwen Zhu, Junliang Chen, Yifei Feng, Yong Xu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-06-01
Schriftenreihe:Frontiers in Cell and Developmental Biology
Schlagworte:
transcriptional regulation
epigenetics
H3K9 methylation
histone demethylation
lysine demethylase
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcell.2021.617549/full
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