Molecular model of TFIIH recruitment to the transcription-coupled repair machinery
Abstract Transcription-coupled repair (TCR) is a vital nucleotide excision repair sub-pathway that removes DNA lesions from actively transcribed DNA strands. Binding of CSB to lesion-stalled RNA Polymerase II (Pol II) initiates TCR by triggering the recruitment of downstream repair factors. Yet it r...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2025-03-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-025-57593-0 |
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