Large-scale meta- and cross-trait analyses uncover shared genetic risk factors for IBS and psychiatric disorders

IntroductionIrritable bowel syndrome (IBS) is a common gut-brain axis disorder characterized by abdominal pain and altered bowel habits, and it shows high comorbidity with psychiatric disorders. However, the shared genetic mechanisms underlying these associations remain incompletely understood.Metho...

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Prif Awduron:	Weiyi Ye, Huanxin Ding, Bichen Peng, Xianjin Wang, Yugang Cheng, Guangyong Zhang, Hongwei Yu, Kalim Ullah, Xiao Chang, Xiaoyan Wang, Zhiyu Wang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2026-05-01
Cyfres:	Frontiers in Psychiatry
Pynciau:	eQTL genetic correlation gut-brain axis irritable bowel syndrome mQTL MTAG
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1795532/full
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