The intricate mechanism of PLS3 in bone homeostasis and disease
Since our discovery in 2013 that genetic defects in PLS3 lead to bone fragility, the mechanistic details of this process have remained obscure. It has been established that PLS3 variants cause syndromic and nonsyndromic osteoporosis as well as osteoarthritis. PLS3 codes for an actin-bundling protein...
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| Huvudupphov: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Frontiers Media S.A.
2023-07-01
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| Serie: | Frontiers in Endocrinology |
| Ämnen: | |
| Länkar: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1168306/full |
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