Genetically engineered Streptomyces viridosporus ATCC 14672 strains for the discovery of novel moenomycins

Abstract Streptomyces viridosporus (formerly ghanaensis) ATCC14672 is the best-studied producer of moenomycins, a family of phosphoglycolipid natural products directly inhibiting peptidoglycan glycosyltransferases. The uniqueness of moenomycins, in terms of structure and mode of action, and their ex...

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Hlavní autoři:	Bohdan Ostash, Roman Makitrynskyy, Mariana Fedchyshyn, Andriy Luzhetskyy, Suzanne Walker, Victor Fedorenko
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-03-01
Edice:	Scientific Reports
Témata:	Antibiotics Moenomycins Genes Streptomyces Genetic engineering Natural products
On-line přístup:	https://doi.org/10.1038/s41598-026-43988-6
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