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TMBIM6 deficiency leads to bone loss by accelerating osteoclastogenesis

TMBIM6 is an endoplasmic reticulum (ER) protein that modulates various physiological and pathological processes, including metabolism and cancer. However, its involvement in bone remodeling has not been investigated. In this study, we demonstrate that TMBIM6 serves as a crucial negative regulator of...

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Bibliografische Detailangaben
Hauptverfasser: Sun-Ju Yi, You-Jee Jang, Seokchan Lee, Sung-Jin Cho, Kyuho Kang, Jae-Il Park, Han-Jung Chae, Hyung-Ryong Kim, Kyunghwan Kim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-08-01
Schriftenreihe:Redox Biology
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2213231723002057
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