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Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study

Abstract Background The genetic changes underlying carcinogenesis in patients with risk factors of gallbladder carcinoma (GBC) remains controversial, especially in patients with pancreaticobiliary maljunction (PBM). This study aimed to clarify the association between risk factors of GBC and genetic...

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Principais autores: Satoshi Kawakami, Shinichi Takano, Mitsuharu Fukasawa, Hiroko Shindo, Ei Takahashi, Yoshimitsu Fukasawa, Hiroshi Hayakawa, Natsuhiko Kuratomi, Makoto Kadokura, Naohiro Hosomura, Hidetake Amemiya, Hiromichi Kawaida, Hiroshi Kono, Shinya Maekawa, Daisuke Ichikawa, Nobuyuki Enomoto
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-11-01
coleção:BMC Cancer
Assuntos:
Gallbladder cancer
Pancreaticobiliary maljunction
TP53
Next-generation sequencing
Acesso em linha:https://doi.org/10.1186/s12885-021-09000-2
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