An Engineered IFNγ-Antibody Fusion Protein with Improved Tumor-Homing Properties

Interferon-gamma (IFNγ) is one of the central cytokines produced by the innate and adaptive immune systems. IFNγ directly favors tumor growth control by enhancing the immunogenicity of tumor cells, induces IP-10 secretion facilitating (CXCR3+) immune cell infiltration, and can prime macrophages to a...

Descripción completa

Detalles Bibliográficos

Autores principales:	Cesare Di Nitto, Ettore Gilardoni, Jacqueline Mock, Lisa Nadal, Tobias Weiss, Michael Weller, Frauke Seehusen, Chiara Libbra, Emanuele Puca, Dario Neri, Roberto De Luca
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-01-01
Colección:	Pharmaceutics
Materias:	interferon-gamma antibody fusion proteins protein engineering cytokines immunotherapy
Acceso en línea:	https://www.mdpi.com/1999-4923/15/2/377
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!