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Cyclic Mechanical Stresses Alter Erythrocyte Membrane Composition and Microstructure and Trigger Macrophage Phagocytosis

Abstract Red blood cells (RBCs) are cleared from the circulation when they become damaged or display aging signals targeted by macrophages. This process occurs mainly in the spleen, where blood flows through submicrometric constrictions called inter‐endothelial slits (IES), subjecting RBCs to large‐...

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Principais autores: Antoni Garcia‐Herreros, Yi‐Ting Yeh, Zhangli Peng, Juan C. del Álamo
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley 2022-07-01
סדרה:Advanced Science
נושאים:
cell aging
inter endothelial slits
microfluidics
red blood cells
red blood cell biomechanics
vesiculation
גישה מקוונת:https://doi.org/10.1002/advs.202201481
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