Targeting Fibrotic Scarring by Mechanoregulation of Il11ra1+/Itga11+ Fibroblast Patterning Promotes Axon Growth after Spinal Cord Injury

Abstract Fibrotic scarring remains a critic obstacle to axonal regeneration after spinal cord injury (SCI). Current strategies primarily concentrating on eliminating extracellular matrix (ECM) components neglect their dispensable roles in maintaining tissue integrity. Here, it is reported that the m...

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Detalhes bibliográficos

Principais autores:	Longyou Xiao, Kaixi Shi, Wen Li, Jialin Liu, Pengfei Xie, Zijun Hu, Yu Dai, Haiyan Weng, Qiuju Yuan, Wutian Wu, Limin Rong, Liumin He
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-11-01
Colecção:	Advanced Science
Assuntos:	aligned migration fibrotic scarring hydrogel mechanical strength mechanotransduction
Acesso em linha:	https://doi.org/10.1002/advs.202513476
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