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High tissue expression of TLRs combined with high density of tumor infiltrating lymphocytes predicts a better prognosis in colorectal cancer patients.

<h4>Background</h4>Colorectal cancer causes 935,000 cancer deaths yearly. High local immune cell infiltration serves as a positive prognostic factor in CRC. Toll-like receptors (TLRs) induce innate immune responses and lead to adaptive immune system activation. TLRs play protumorigenic and antitumor...

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Principais autores: Ines Beilmann-Lehtonen, Jussi Kasurinen, Jaana Hagström, Tuomas Kaprio, Camilla Böckelman, Caj Haglund
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2023-01-01
coleção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0280085
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