Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability

The cytotrophoblast of human placenta transitions into an outer multinucleated syncytiotrophoblast (STB) layer that covers chorionic villi which are in contact with maternal blood in the intervillous space. During pregnancy, the Zika virus (ZIKV) poses a serious prenatal threat. STB cells are resist...

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Detalhes bibliográficos

Principais autores:	Jael Miranda, Dolores Martín-Tapia, Yolotzin Valdespino-Vázquez, Lourdes Alarcón, Aurora Espejel-Nuñez, Mario Guzmán-Huerta, José Esteban Muñoz-Medina, Mineko Shibayama, Bibiana Chávez-Munguía, Guadalupe Estrada-Gutiérrez, Samuel Lievano, Juan Ernesto Ludert, Lorenza González-Mariscal
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2019-09-01
coleção:	Cells
Assuntos:	zika virus flavivirus tight junctions claudins zo-1 blood-placental barrier placenta
Acesso em linha:	https://www.mdpi.com/2073-4409/8/10/1174
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