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Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones

In this study, new chalcone compounds having the chemical structure of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones (1–8) were synthesised and were characterised by 1H-NMR, 13 C-NMR, and HRMS spectra. Cytotoxic and carbonic anhydrase (CA) inhibitory effects of the compounds were investigated. Cytotox...

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Principais autores: Sinan Bilginer, Halise Inci Gul, Feyza Sena Erdal, Hiroshi Sakagami, Serkan Levent, Ilhami Gulcin, Claudiu T. Supuran
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2019-01-01
coleção:Journal of Enzyme Inhibition and Medicinal Chemistry
Assuntos:
anticancer
benzoxazolone
carbonic anhydrase
chalcone
cytotoxic
Acesso em linha:http://dx.doi.org/10.1080/14756366.2019.1670657
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