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Generation of a CFTR knock-in reporter cell line (MHHi006-A-1) from a human induced pluripotent stem cell line

CFTR encodes for a chloride ion channel expressed primarily in secretory epithelia in the airways, intestine, liver and other tissues. Mutations in the CFTR gene have been identified in people suffering from Cystic Fibrosis. Here, we established a CFTR knock-in reporter cell line from a human iPSC l...

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Autori principali: Lena Engels, Ruth Olmer, Jeanne de la Roche, Gudrun Göhring, Saskia Ulrich, Ralf Haller, Ulrich Martin, Sylvia Merkert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019-10-01
Serie:Stem Cell Research
Accesso online:http://www.sciencedirect.com/science/article/pii/S1873506119301722
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