Lithium Induces Oxidative Stress, Apoptotic Cell Death, and G2/M Phase Cell Cycle Arrest in A549 Lung Cancer Cells

Lithium has been identified more than six decades ago as a preferred treatment option for manic depression. Due to its affordability, stability, minimal side effects, and immunomodulatory effects, recent studies on lithium have focused on its potential anticancer properties and possible mechanisms o...

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Main Authors: Pearl Ramushu, Dikgale D. Mangoakoane, Raymond T. Makola, Thabe M. Matsebatlela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-04-01
Colecção:Molecules
Assuntos:
lithium chloride
lung cancer
oxidative stress
apoptosis
cell cycle arrest
Acesso em linha:https://www.mdpi.com/1420-3049/30/8/1797
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